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Research shows patients typically regain 50-80% of lost weight within 6-12 months after discontinuing treatment

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Results highlighted that liraglutide induced significant weight loss but did not reduce knee pain compared to placebo [48]

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Long-term use may be required to maintain weight loss, which has cost and ongoing commitment implications

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This guidance follows the FDAs approval of Wegovy (semaglutide) for an expanded indication to reduce the risk of major cardiovascular events (MACE), including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in adults with established cardiovascular disease (CVD) and who are either obese or overweight

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