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A structurally identical GLP-1R has been identified in various tissues, for example: pancreatic tissue (alpha-, beta-, delta-cells), stomach, and intestine, as well as CNS regions including the hypothalamus and brainstem ( (81, 93)

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SLU-PP-332 activates all three ERR isoforms with high potency, with EC50 values of approximately 98 nM for ERR, 230 nM for ERR, and 430 nM for ERR, making it among the most potent pan-ERR agonists available for research