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Prospective cohorts, such as Dao et al , improve validity through standardized definitions, but remain underpowered to detect rare anomalies

The obesity and type 2 diabetes mellitus epidemics have prompted expanded use of incretin-based therapies

The FDA labeling recommends considering dose reduction of insulin or sulfonylureas when initiating tirzepatide to mitigate this risk

Pre-pregnancy treatment of semaglutide improves high-fat-diet-induced placental and fetal hypothalamic alterations in a sex-specific manner in rats

Eliminate bladder irritants, including caffeine, alcohol, citrus, and spicy foods, for two weeks to see if symptoms resolve