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However, because the results of clinical phase III programmes are often published in a selective manner, and because published manuscripts on clinical trials sometimes do not contain sufficient information on rare adverse effects, we believe that this approach provides a more complete and unbiased assessment

Without adequate protein, you risk losing muscle along with fat which undermines the metabolic benefits of your weight loss

They work by mimicking the action of naturally occurring GLP-1, an incretin hormone released from the intestine in response to food intake

doi: 10.1161/CIRCULATIONAHA.118.038771

Therefore, reducing fat deposition through GIP receptor antagonism still hold promising therapeutic potential supported by animal models and the fact that individuals with loss-of-function GIPR genetic variants have a lower body mass index (BMI) (39, 9799)