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Description
Presented at #ECO2025: In the SURMOUNT-5 phase 3b trial involving adults with obesity without type 2 diabetes, tirzepatide was superior to semaglutide in reducing body weight and waist circumference
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Take-home message: GLP-1 medicines improve MASH through both systemic metabolic effects and direct, liver-specific mechanisms, with LSECs emerging as a central regulatory hub
