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De Giorgi and colleagues present a comprehensive analysis of pre-clinical and clinical studies examining the role of glucagon-like peptide-1 receptor agonists in mental disorders.

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rRYGB yields a modest mid-term %EWL advantage up to 3 years, of about 3 to 4% points, without a clear 5-year benefit, while increasing vomiting risk and showing a preliminary signal of higher re-operation, with no evident comorbidity or overall quality-of-life advantage

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