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J Investig Med

Most clinical trials measured outcomes at 68 weeks, highlighting that this is a long-term intervention

Excessive supplementation of certain vitamins and minerals can cause toxicity and adverse effects
Bedrosian notes that while bariatric surgery remains the gold standard for weight loss, medications like Ozempic and Wegovy, as well as Mounjaro (FDA-approved to treat type 2 diabetes) and Zepbound (FDA-approved for weight loss) offer a valuable option for individuals who don't qualify for or aren't interested in surgery

A reasonable discontinuation protocol involves reducing dose by one tier every 4 to 6 weeks while intensifying dietary control and physical activity
