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Hype Lately, theres been a lot of buzz about natural GLP-1s - meaning, natural options that supposedly have similar weight-loss promoting effects as GLP-1 receptor agonist (GLP-1 RA) medications

For example, chitosan, chitooligosaccharides, and chitosan-derivates have demonstrated anti-obesogenic effects through different mechanisms: inhibition of PPAR-, stimulation of glucokinase, reduction of leptin, adiponectin, and resistin levels, inhibition of adipogenesis, lipid metabolism modulation, and suppression of phosphoenolpyruvate carboxylase (Shagdarova et al., 2023)

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