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The peptide agonist retains an -helical conformation as it sits deep within the receptor-binding pocket

: #neuromodulation #clinicaltrials #painmanagement #medicaldevices #reimbursement To view or add a comment, sign in Safety Outcomes from Early Studies In Aqua Medicals early feasibility studies of the investigational Proximal Intestinal Mucosal Ablation (PIMA) procedure, researchers have observed: Zero device- or procedure-related serious adverse events reported to date across 66 patients treated in Santiago, Chile Low levels of post-procedure discomfort, typically resolving by day 3 Well-tolerated across study cohorts, including patients on oral agents, insulin users, and retreatment cases Repeatable outcomes, without the need for surgery or fluoroscopy Why it matters: A promising safety profile, paired with early signs of metabolic benefit, suggest that a through-the-endoscope approach may offer a third path in Type 2 Diabetes care

not approved, research-only

Zhaoping Li, professor of medicine and chief of the division of clinical nutrition at the University of California, Los Angeles, prescribes Wegovy as a second-line therapy for patients with obesity who can't lose or maintain weight with diet, exercise and other lifestyle changes

Notes from GLP-1 Match Emerge Weight Loss (Emerge) focuses on a single goal: providing patients with reliable, affordable access to compounded tirzepatide