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DISCUSSION In two large clinical trials, in which semaglutide was used to treat different patient groups for which NAFLD is a known comorbidity, there were clear dosedependent reductions in both ALT and hsCRP

GLP-1 medications like Zepbound, Wegovy, and Ozempic are known for quieting it, often within days of the first dose for many people it's the first time they realize how loud it was

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Also, this group had withdrawal assistance to assess any change in weight due to switching from the semaglutide to a placebo