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PMID: 36789109

Al-Badri MR, Azar ST

You may find your weight loss kickstarts again after you settle back into your routine
Approximately equal numbers of patients were randomized to receive placebo, 100 mg of sitagliptin once daily, 500 mg or 1000 mg of metformin HCl twice daily, or 50 mg of sitagliptin twice daily in combination with 500 mg or 1000 mg of metformin HCl twice daily

Because this compound engages three distinct hormonal pathways-GLP-1, GIP, and glucagon-investigators built intensive monitoring schedules into the phase 2 trial designs
