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doi: 10.1111/dom.12881

Wegovy is also FDA-approved to treat metabolic dysfunction-associated steatohepatitis (MASH), a condition that causes inflammation and scarring in the liver, including more serious scarring called advanced fibrosis

Although its blood pressure-lowering effects appear to be less than spironalactone and eplerenone (both steroidal mineralocorticoid receptor antagonists), this drug has impressive benefits in the setting of DKD

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In the brain, the interaction of GLP-1 or GLP-1RA with the GLP-1R additionally contributes to multi-level control of neuroplasticity mechanisms thus having potential cognitive and affective effects