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Description
Support for Metabolism : Micro-dosing GLP-1s can help prevent the metabolic slowdown that often accompanies significant weight loss, supporting better energy balance and fat burning

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Toxicon: official journal of the International Society on Toxinology 60, 596602, doi: 10.1016/j.toxicon.2012.05.027 (2012)

If a meaningful subset is metabolic OA, driven by insulin resistance and inflammation, then disease modification may require metabolic therapeutics, not just braces and injections
Brain imaging of the GLP-1 receptor in obesity using (68)Ga-NODAGA-Exendin-4 PET