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Interestingly, improvements in anxiety-like behavior after loss of GLP-1R were only noted in females, potentially suggesting females rely more on this system to maintain a baseline of normal anxiety-like behavior (113)

doi: 10.1016/S0140-6736(24)02808-3

Cardiovascular Safety During and After Use of Phentermine and Topiramate

GLP-1 receptor agonists show no significant link to major birth defects in pregnancy, but urinary malformation findings call for caution and more research

A full medical evaluation is required before starting any treatment
