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The risk of bleeding has not been a frequent topic of consideration or discussion amongst clinicians [139], but as previously summarized the GLP-1R agonists do have antithrombotic properties

Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents

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Right now, there are two studies that can shed some light on this: Controlled lab trial (JAMA Psychiatry, 2025) Researchers gave weekly semaglutide injections to 48 adults diagnosed with Alcohol Use Disorder (AUD), meaning they drank at least 7 drinks per week (women) or 14 drinks per week (men), and had at least two heavy-drinking episodes per month (4+ drinks per sitting for women, 5+ for men)

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