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(Weinh) 12, e2405263

Measurement of flow velocity across a stenosis can be used to estimate trans-stenotic pressure gradients analogous to echocardiographic spectral doppler however gradients may be underestimated due to decreased temporal resolution of CMR imaging (peak velocity through region of interest can be missed) or imaging plane not being at the vena contracta (a higher velocity may be obtained at a higher or lower imaging plane)

If results from a research chemical product fall significantly below what clinical trials show for pharmaceutical semaglutide at equivalent doses, product quality is the most likely explanation

Travel, schedule changes, and medical procedures are common reasons for missed doses