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27 LiuY.WangY.HeX.ZhangS.WangK.WuH.et al (2018)

2025;199:5763 Why might GLP-1RAs help in ovarian cancer

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Microvascular endothelial cells (CMECs) were isolated from neonatal SpragueDawley (SD) rat hearts by the enzyme dissociation to induce hypoxia/reoxygenation (H/R) injury, and GLP-1 analogue liraglutide protected cardial microvascular endothelium from H/R injury by activating PI3K/Akt/survivin pathways (68).Liraglutide-induced PI3K activation was also able to enhance keratinocyte migration and promote wound healing in mice (9)

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