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Acta pharmacologica Sinica

In the absence of head-to-head comparisons, indirect evidence across heterogeneous trial populations with placebo or inferior active comparators provides limited guidance for clinical decision-making

Understanding how these incretin-based therapies interact with your gastrointestinal system helps explain their common digestive side effects
For rheumatoid arthritis, the American College of Rheumatology recommends disease-modifying antirheumatic drugs (DMARDs) as first-line therapy, with methotrexate being the most commonly prescribed conventional synthetic DMARD

Indeed, the frequency of the adverse events in the exenatide group appeared to be analogous to that reported in prior clinical trials of exenatide in T2DM
