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This cohort study uses emulation target trial methods to evaluate whether semaglutide is associated with lower rates of opioid overdose among patients with type 2 diabetes (T2D) and opioid use disorder (OUD).

Heart protection: in the SELECT trial, semaglutide cut major cardiac events (heart attack, stroke, cardiovascular death) by about 20% in people with obesity and heart disease but no diabetes

Does semaglutide cause body odor