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Bunck, M.C., et al

GLP-1 receptor agonists and dual GLP-1/GIP co-agonists can produce substantial weight loss, but caloric restriction and weight loss trigger adaptive thermogenesis and neuroendocrine changes (reduced energy expenditure and increased appetite) that facilitate weight regain once therapy is discontinued
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Danvers, MA, USA), Rabbit anti-DLL3 (#71804, Cell Signaling

These two medicines are working on the problem from different angles
