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Compounding pharmacies operate under state pharmaceutical regulation and, for facilities meeting certain thresholds, under FDA oversight of the facility itself (503A and 503B designations)
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It plays a pivotal role in energy balance and postprandial metabolism by enhancing glucose-dependent insulin secretion, suppressing glucagon release, delaying gastric emptying, and promoting satiety through central mechanisms [8, 9]

The REWIND trial with dulaglutide and SUSTAIN-6 with semaglutide also demonstrated cardiovascular benefits

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