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The primary mechanism involves binding to GLP-1 receptors in specific areas of the brain, particularly the hypothalamus and brainstem regions that regulate hunger and satiety

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In contrast, bitter foods activate a different set of receptors (called TAS2Rs), which have been shown to stimulate the release of key digestive hormones, including GLP1 and ghrelin (which regulates hunger and satiety)

GLP-1 receptor agonists, liraglutide and lixisenatide, also display neuroprotective properties in MPTP mouse models
