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The tobacco blend is treated with steam and water to optimise moisture
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These adverse effects are thought to be mediated by the endocannabinoid system (ECS), which comprises lipid-derived neurotransmitters (endocannabinoids) and their receptors (CB1 and CB2), which are expressed throughout the hypothalamicpituitarygonadal (HPG) axis 5,7
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The brain gradually returns to a more stable state of functioning without continuous artificial stimulation
