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Description
3 weeks to 3 months Your circulation has substantially improved

On average, you get about 200 to 300 puffs out of a standard 20-count pack of cigarettes
Prolonged exposure can trigger headaches, allergies, or respiratory issues, particularly for children, asthmatics, or those with sensitive lungs

Food and Drug Administration (FDA) on how flavors and sweeteners in tobacco products affect their addictive properties

One possible etiology is found in the flavorants added to the liquid, specifically diacetyl and 2,3-pentanediol, which have been shown to change gene expression of cilia on the bronchial epithelium in the respiratory mucosa (5)
