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As this genetic disease is recessive, this variant can only confer susceptibility to optic neuropathy, but it could act synergistically with the SPG7 variant to increase susceptibility to optic nerve damage

This governments plan to introduce smoke-free generation legislation could become its defining legacy, righting a century-old wrong, with tobacco products being the only legally available commodity that, if used as intended, will kill over half of its lifelong users, said Lion Shahab, an academic who co-directs the tobacco and alcohol research group at University College London

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