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Short Answer: Yes smoking can absolutely cause a sore throat, as hot smoke and toxic chemicals irritate and inflame the throat lining, potentially leading to chronic pain and even serious conditions if exposure continues

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Expiratory carbon monoxide (CO) levels of all subjects were measured using the Smokerlyzer System (Bedfont Scientific, Limited, Rochester, UK

A study of 10 male and 4 female volunteers who were administered glycerol in orange juice with each meal at a dose of 1.3 to 2.2 g/kg/day for 50 days reported no evidence of toxicity or adverse effects on blood or urine production