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These observations align well with the concept of Anna Karenina principle for animal microbiomes (Zaneveld et al., 2017), which refer to a more variable microbial community composition in dysbiotic individuals compared to healthy individuals

In accordance, our group has previously demonstrated a Th2 driven immune responses in asthmatic children exposed to parental tobacco smoke [279]

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Microbiological contamination of SLT along with the impact of varying climatic and geographic conditions might pose an additional risk by altering the nature of the intended constituents of the packaged SLT product

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