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Aldehydes (formaldehyde, acetaldehyde) are important toxic components in cigarette smoke, resulting in an equivalence of 1 cig/week during the burning season in Chiang Mai while Bangkok and Beijing do not have such high values but have higher annual averages

Periconception smoking has recently been reported (Am J Obstet Gynecol 2019;220:588) to be associated with a higher risk of congenital birth defects including neural tube defects with associated central nervous system abnormalities and other fetal malformations including limb reduction, cleft palate and gastrointestinal defects

Of that group, 64% reported two or more courses