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Description
Late sequelae of superficial frostbite include cold hypersensitivity (53%), numbness (40%), decreased sensation (33%), and impaired ability to work (13%)

Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products
MUDO Sat Maazalar A., farkl MUDO Sat Maazalar A.

Research indicates that smoking approximately doubles the risk of stomach cancer, particularly affecting the upper part of the stomach near the esophagus, known as the gastric cardia

Although there are current concerns around safety and lack of industry regulation, if these can be addressed, this may hold significant promise for refractory smokers in particular