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There is also a causal relationship between cigarette smoking and cancers of the head, neck, liver, bladder, cervix, esophagus, colon, and rectum [9]

Thorax 36 , 366369 (1981)

However, like other recent psychiatric MR studies where the exposure instruments included a relaxed statistical threshold, our binge drinking and AUD instruments were comprised of independent SNPs associated with the respective drinking behavior (i.e., P -value 0.001, leaving 141 and 126 MV instruments, respectively (Supplementary Data 5 and 6)