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Although these particular flavors are Generally Regarded As Safe by the Flavor Extract Manufacturers Association (FEMA) for ingestion, FEMA has not evaluated them for inhalation toxicity. They conclude: It is important for the FDA to identify and quantify flavor chemicals before authorizing Premarket Tobacco Applications (PMTA) for two reasons

And not in a good way

If you know youre done with one hard milestone, it helps build your confidence and affirm your determination to go smoke-free

Russell was not entirely correct, however

The findings of this study can be leveraged to enhance public health by identifying harmful chemicals that exceed established limits and potentially motivating manufacturers to produce less harmful products by conforming to toxicant emission standards