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[9] Arsenic is a neurotoxin capable of crossing the blood-brain barrier and accumulating in the brain and, as such, neurological complications are often present which may include seizures, comatose state, and severely reduced cognitive functioning

Nicotine from the wrap adds a stimulant layer a head rush that combines with the THC response and makes the overall experience feel heavier and more intense, even if the THC delivery is technically lower

Shadel WG, Martino SC, Setodji CM, Dunbar M, Scharf D, Creswell KG

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[12] On the colonial charters and states constitutions see Conrad Henry Moehlman, The American Constitutions and Religion