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With research gaining more widespread exposure, the tobacco industry recognized a threat to sales and began a campaign to fight the science

Here are some key points regarding the health effects of nicotine and tobacco products: A ddiction: Nicotine is a highly addictive substance

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Eighty articles were excluded because they were not relevant, were not in English, or were reviews or commentaries that did not provide original data, although some are cited for background and context

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