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They refer to a medical study in 2010 that suggested social relationships, or the relative lack thereof, constitute a major risk factor for healthrivalling the effect of well established health risk factors such as cigarette smoking - though we couldnt find any mention of 15 cigarettes.* To reach their figure of 100 million deaths in the 20th century, WHO looked at the prevalence of tobacco use in each country, the risk of death among tobacco users and the total number of deaths in a population

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Heated tobacco such as IQOS use real tobacco which means the nicotine delivery is similar to cigarettes

A direct exposure was defined as ingesting nicotine pulmonarily (e.g., smoking a cigarette, cigar, or pipe), or buccally (chewing smokeless tobacco)

Natalia Szejko, Medical University of Warsaw, Poland Updates Copyright 2022 Zeng, Lv, Li, Xue, Liu, Zhou and Yu