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42 FDA then opened a public docket in November 2017 to allow for comment on these proposed ENDS GMPs, 43 but the agency has not taken further action since then

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Both the tested doses of sodium arsenite induced statistically significant micronucleated polychromatic erythrocytes as compared to control group, however, sodium arsenite and smokeless tobacco extract could not increase the incidence of micronucleated polychromatic erythrocytes as compared to their individual counterparts when treated in combination in mice test system

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