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That particular take-away is made extremely clear in the chart

It was considered a specialty item until 1954, when manufacturers introduced the machine more broadly, following a spate of announcements from doctors and researchers concerning a possible link between lung diseases and smoking

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4 In one study, the liquid solution from four of the top 10 brands was tested and found to contain over 115 volatile chemical compounds, as well as many others that were produced when the liquid was heated

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