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After CVSs tobacco removal, household- and population-level cigarette purchasing declined significantly, the study concluded

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Ac- cording to the International Cannabis Consortium and the Tobacco and Genetics Consortium, polygenic risk scores for cigarettes per day are positively associated with lifetime e-cigarette use and early initiation of wa- ter pipe use, but only in ex-smokers (Odds Ratio [OR] = 1.4, R2=1.56%, p = 0.011) and never cigarette smok- ers (OR = 1.35, R2 = 1.6%, p = 0.013), respectively25

This sound production is believed to be a type of acoustic aposematism, or warning sounds that let predators know that trying to eat them will be troublesome