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Basically the same as mainland American time zones

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Among the key factors that could cause actual results to differ materially from those projected in the forward-looking statements are uncertainties related to the following: the impact of competition from illicit trade

2017;26:e68e70

As a systematic review by the Cochrane Library noted: The small number of trials, low event rates and wide confidence intervals around the estimates mean that our confidence in the result is rated low. For example, there were weaknesses in the randomized trials