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We did not observe this effect with the same concentration of nicotine alone in the short-term experiments, but we could observe the dose-dependent inhibitory effect of nicotine on cellular metabolism already at 50 ng/mL and 100 ng/mL in the long-term exposure (21 days)

Second, the study demonstrates flexibility by employing two distinct approaches in deriving the model, with multiplicative regression using log transformation yielding a straightforward equation