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Description
In addition to oxidation of the pyrrolidine ring, nicotine is metabolized by two nonoxidative pathways, methylation of the pyridine nitrogen giving nicotine isomethonium ion (also called N -methylnicotinium ion) and glucuronidation
They also increase the risk of thrombosis and so on
In This is just a general rule of thumb though
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Jacob p, 3rd (2004)
