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In the same study, a promotion of M2-like macrophages was shown in the airway lumen of COPD patients with smoking history, whereas abundant M1-like macrophages were observed in the airway wall (21)

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Unpaired two-tailed t -tests were used comparing smoke-mediated parthanatos activation in HBE cells from smokers and non-smokers, and the Mann Whitney test to compare PARP1 expression levels

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By addressing this aspect, it becomes easier to manage situations where cigarettes and tension are usually associated
