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Arguably, the gravest concern public health experts share is that the FDAs authorization may not only send nicotine addiction rates soaring but also push e-cigarette users to seek other nicotine-delivery products, such as traditional cigarettes, pipes, pipettes, and smokeless tobacco to get their nicotine fix

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from e-cigarettes or HNB) induces oxidative stress, nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX-2 activation), and eNOS uncoupling

Cigarettes also contain nicotine, which is a stimulant