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The UK Chief Medical Officers recommend that if you are pregnant or planning to become pregnant, the safest approach is not to drink alcohol at all to keep risks to your baby to a minimum

Smoking tobacco contributes to several different types of cancer, including lung, oral and nasopharynx (nose and throat) cancer

Perhaps the most socially acceptable form of self-medication is caffeine

One study in ADHD patients showed that transdermal nicotine (7 mg/day) improved clinical global impressions of ADHD symptomatology while it increased self-ratings of positive affect

It doesnt just work on the face, it can be used anywhere on the body, for example for those wrinkly batwings