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THC (tetrahydrocannabinol) also interacts with the receptors of the cardiovascular system, causing inflammation in the blood vessels, which can lead to heart rhythm abnormalities like tachycardia, atrial fibrillation, and other subsequent cardiovascular diseases

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Typically, you can use one spray when you feel the urge to smoke or vape

However, it is important to remember that rescheduling does not legalise or even decriminalise cannabis

Although NOTCH signaling drives secretory cell fate in the differentiating airway epithelium 21,22 , and the transcription factor (TF), SPDEF 23,24 , specifically drives inflammation-induced mucus metaplasia, converting club cells into mucus cells in mice 25 , little else is known regarding regulation of human secretory cell development