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Smoking, fat mass and activation of the tumor necrosis factor-alpha pathway

[45,46] On the other hand, chronic smoking is associated with dysfunction of the autonomic nervous system, [47-49] and the abnormal HR responses to tobacco may be implicated in the link between smoking and cardiovascular disease

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We demonstrate that, similar to acrolein or combustible cigarette smoke, aerosols from e-cigarette solvents (vegetable glycerin and propylene glycol) induce bradycardia, bradyarrhythmias, and elevations in heart rate variability during inhalation exposure, with inverse post-exposure effects