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Commonly prescribed serotonergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs), venlafaxine and trazodone, do not improve common psychological symptoms in people with substance use disorders, including alcohol use disorder

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In a randomized crossover trial comparing healthy subjects who smoked tobacco (maximum of 10 cigarettes per month), the acute use of nicotine-containing e-cigarettes significantly increased levels of circulating endothelial progenitor cells (flow cytometry) to the same magnitude as after smoking a traditional cigarette (41)

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