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More studies have found that arginine methyltransferase-1 participates in the pathogenesis of epithelial tract injury in COPD by adding methyl to arginine residues in histones and non-histones to regulate protein modification at post-translational levels [64]

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Last year, the anti-smoking group Truth Initiative found that on-screen depiction of tobacco increased for the first time since 2002, with smoking shown in 80% of the 2025 Oscar best picture nominees, according to The Ankler