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For example, HPV vaccination is currently available only from the SUS [ Sistema nico de Sade, Brazils national health service ] for children aged 9-14 because studies have evidenced its efficacy against genital pathologies, but I believe it should be possible to consider extending the age group in order to prevent diseases in other anatomical regions. This study in particular, he added, translates the results obtained in the laboratory to clinical analysis by surmounting the Achilles heel of basic research, which is the difficulty of access to human samples, thanks to technological advances leading to the creation of databases for human samples like the one used in the study

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Rdiger Krech, director of the WHO Department of Health Promotion

Conditional recommendations are made when the certainty of evidence is lower, when the margin between desirable and undesirable consequences is small and the balance depends on patient values and preferences, or when there is high variability in the values and preferences of patients