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We need a range of evidence-based options for people to use to quit smoking, as some people will try many different ways of quitting before finding one that works for them. Hartmann-Boyce, a Cochrane editor, is senior author of the review, which included 88 studies and more than 27,235 participants-an addition of 10 studies since the last update in 2022

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Upper-lobe predominance of emphysema was also more common in combined smokers, seen in 55% of them versus 32% in tobacco-only smokers (Pradre et al., 2026)