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VLN cigarettes could be on the market in as many as 18 US states within the next 12 months, manufacturer 22nd Century Group said during the presentation of its third quarter results

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According to 22nd Century, government-funded research is trying to answer a number of questions about low-nicotine cigarettes, including how different nicotine levels in cigarettes affect smoking behavior, at what level nicotine is no longer addictive and whether a gradual or an immediate reduction in cigarettes' nicotine content to non-addictive levels is more favorable for smokers

Experts believe lobeline, the active ingredient in the lobelia plant, works by binding to the same receptor sites in the brain as nicotine

Tolerance to cigarettes should be built up gradually